Influence of the spaceflight environment on macrophage lineages
- An R, Blackwell VK, Harandi B, Gibbons AC, Siu O, Irby I, Rees A, Cornejal N, Sattler KM, Sheng T, Syracuse NC, Loftus D, Santa Maria SR, Cekanaviciute E, Reinsch SS, Ray HE, Paul AM
- June 11, 2024
This important new report provides guidance on how to share information about studies involving human participants, with a special focus on sex and gender. The researchers behind this work believe that understanding these factors is crucial for improving health outcomes because they can influence the way diseases affect people differently based on their biological characteristics. The paper emphasizes that when scientists report findings from studies involving humans, it's essential to include details about who participated in those studies and how sex and gender may have played a role. This information helps ensure transparency and allows other researchers to learn more effectively by comparing results across different groups of people with diverse backgrounds. The study also highlights the need for better reporting practices, as many scientific papers currently do not provide enough details about participants' sex or gender identity in their findings. This lack of information can make it difficult for others to understand how research outcomes might apply specifically to men and women (or non-binary individuals) differently. In summary, this report calls on the scientific community to adopt more comprehensive reporting standards when sharing results from human studies involving sex and gender differences.
Title: Investigating Sex, Gender, and Policy Information Disclosure in Human Research Studies Abstract (Summary): This research paper examines the importance of reporting sex and gender information within studies involving human participants. The study highlights that comprehensive disclosure is not only a matter of scientific transparency but also essential for understanding biological differences among genders, which can significantly impact health outcomes and treatment efficacy. Methodology: To investigate this issue, the researchers conducted an extensive literature review focusing on studies published in peer-reviewed journals that included human participants with varying sexes and gender identities over a 10-year period (2010-2decade end). The inclusion criteria were as follows: 1. Studies must have been designed to investigate the impact of biological differences between genders on health outcomes or treatment efficacy, using human participants with diverse sex and gender identities. 2. Only studies that reported detailed information about participant demographics (sex and/inferred gender) were included in this review. 3. Studies must have been published within the last decade to ensure relevance of findings for current research practices.
MLA
R, An, et al. “Influence of the spaceflight environment on macrophage lineages.” PubMed Central, National Center for Biotechnology Information, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166655/. Accessed 30 Sept 2026.
Chicago
R, An, et al. “Influence of the spaceflight environment on macrophage lineages.” PubMed Central. 30 September 2026. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166655/.